Mean spherical equivalent refractive error was -1.34 ± 1.52 (range, -4.00 to +1.50) diopters. The mean age of men and women was no difference (66.13 ± 6.90 vs. The mean age of patients at presentation was 65.14 ± 7.17 (range, 54 to 79) years.
And the 15 bilateral macular hole cases were all women. The sex ratio of men to women was 1:3.36. A total of 113 patients (74.83%) were women. In all, 166 eyes of 151 patients fulfilled the inclusion and exclusion criteria. Statistical significance was set as P < 0.05. Statistical comparison of categorical findings was performed using the chi-square test. Numerical computations were performed using a spreadsheet package (Excel 2010 Microsoft, Redmond, WA). The RB and/or lattice degeneration were recorded. The fundus was carefully inspected by a three-minor Goldmann lens with a dilated pupil. Macular holes were graded using the Gass classification. The status of macular was confirmed by optical coherence tomography (OCT). All the patients received a general ophthalmologic examination. Patients suffering from MH secondary to uveitis, trauma, and high myopia or associated with a simultaneous retinal detachment (RD) were excluded. Lin Lu from January 2009 to December 2013 at the Zhongshan Ophthalmic Center. This study included patients who were diagnosed as full-thickness macular hole and referred to Dr. The Zhongshan Ophthalmic Center Ethics Committee did not require for this study to undergo Internal Review Board (IRB) approval as all the tests carried out were part of the routine care of patients. All patients gave informed consent to being imaged and for the collected data to be used for publication.
#RETINAL ATROPHIC HOLE SERIES#
This is a prospective observational case series study conducted according to the tenets of Declaration of Helsinki. We conducted a prospective observational case series to investigate the relationship between full-thickness macular hole and RB/lattice degeneration. To figure out the relationship between the full-thickness macular hole and RB/lattice degeneration may contribute to the understanding of their pathogenesis. Retinal break (RB) and lattice degeneration are one of the most important abnormalities of vitreous and vitreoretinal interface.
The pathogenesis of full-thickness macular hole (MH) is not clearly understood but is believed to involve anteroposterior traction and/or tangential traction exerted by the posterior vitreous cortex at the fovea. Macular hole, Retinal break, Lattice degeneration, Optical coherence tomography, Vitreous retinopathy Carefully examination of the peripheral retina and prophylactic treatment of retinal breaks and/or lattice degeneration are critical. The inferior quadrants and the vertical meridian were affected more often than the superior quadrants and the horizontal meridian.Ĭonclusion: We identified a high incidence of retinal breaks/lattice degeneration in cases of full-thickness macular hole. All of the RB and/or lattice degeneration were located near or anterior to the equator. The prevalence of RB and/or lattice degeneration was similar between men and women (p = 0.561). RB and/or lattice degeneration were found in 59 eyes (35.54%). Results: Totally 166 eyes of 151 patients were included. All patients underwent general ophthalmologic examinations, fundus examination and optical coherence tomography (OCT). Lin Lu from January 2009 to December 2013 were evaluated. Methods: Patients diagnosed as full-thickness macular hole and referred to Dr. Purpose: To investigate the relationship between full-thickness macular hole and retinal break (RB) and/or lattice degeneration. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (2015) Relationship between Full-Thickness Macular Hole and Retinal Break/Lattice Degeneration. Received: J| Accepted: Aug| Published: September 02, 2015Ĭitation: Zhang J, Li Y, Zhao X, Cai Y, Yu X, et al. *Corresponding author: Lin Lu, MD, Ph.D, The State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China, E-mail: J Ophthalmol Clin Res, IJOCR-2-036, (Volume 2, Issue 5), Research Article ISSN: 2378-346X
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